Nicola Fusco, Director of the Division of Pathology at IEO European Institute of Oncology, shared a post on LinkedIn about a paper he co-authored with colleagues published in Nature Communications:
“Some scientific questions stay with you for a lifetime.
Twelve years ago, I returned to Italy after a life-changing experience at Memorial Sloan Kettering Cancer Center in New York, working with Jorge Reis-Filho. I came back with new skills, a broader perspective, and questions that continued to guide my path.
One of the first research lines I launched as a PI focused on mismatch repair mechanisms in breast cancer. Around the same time, one of my earliest international collaborations began, working with the Svasti Haricharan team in SDSU Biology Department on this very topic.
Today, seeing this collaboration culminate in a newly published paper Nature Communications is energizing. It shows how strong scientific questions evolve, mature, and continue to generate insight over time.
Years pass.
Technologies evolve.
People grow, lead teams, and shape new directions.
But impactful research continues to emerge from shared vision, trust, and long-term collaboration.
There is still much to learn about how MMR perturbations in breast cancer can guide better, more personalized treatment for patients.”
Title: Aberrant cytoplasmic localization of MLH1 characterizes a cell population that seeds breast cancer recurrence
Authors: Aloran Mazumder, Jerry Dewitt, Elena Oropeza, Nindo Punturi, Daniel Lozano, Megha Raghunathan, Jonathan Piscitelli, Elham Sajjadi, Elena GueriniRocco, Konstantinos Venetis, Mariia Ivanova, Eltjona Mane, Marianna Dercole, Alberto Concardi, Nicola Fusco, Carol Manhart, Matthew Bainbridge, Svasti Haricharan
You can read the full article in Nature Communications.
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