Nelson Dusetti, Head of the Translational Research and Innovative Therapies Department at the Cancer Research Centre of Marseille (CRCM), shared a post on LinkedIn:
“Join us at ESMO 2025 in Berlin where we will present our work ‘Comprehensive analysis of treatment-associated dynamics in PDAC reveals drug response patterns and novel mechanisms of cell plasticity linked to chemotherapy resistance’ Presented by Nicolas Fraunhoffer Ph.D.. CRCM – Cancer Research Center of Marseille, and the Institut Paoli-Calmettes (IPC)
By integrating patient-derived models and single-cell transcriptomic data from PDAC patients, we reveal how tumors adapt to chemotherapy and transition toward resistant phenotypes.
These findings underpin PANCprofiler, a predictive deconvolution tool designed to map intratumoral phenotypes and support personalized treatment in pancreatic cancer.
Integrating patient data and functional modeling could significantly advance precision oncology in PDAC.”
Read more posts featuring Nelson Dusetti on OncoDaily.