Myriam Saadi, Medical Oncologist at Abderrahmen Mami Hospital, shared a post by Raouia Ben Amor, Radiation Oncologist at Abderrahmen Mami Hospital, on LinkedIn, adding:
“When access to radiation is limited and delayed, inverting the PORTEC-3 protocol sequence (starting with chemotherapy followed by concurrent chemoradiotherapy) is a safe and effective alternative.
With my friends and colleagues from the radiation oncology department, we invite you to read our freshly published paper in Cancers MDPI.
“Teamwork makes the dream work”
Grateful for amazing colleagues and great collaborations.
To many more meaningful achievements together!”
Quoting Raouia Ben Amor‘s post:
“Proud moment.
Thrilled to share the publication of our work,
“When Standards Meet Reality: An Inverted PORTEC-3 Protocol for High-Risk Endometrial Cancer in Resource-Limited Settings”
in Cancers MDPI.
This paper speaks for oncologists in LMICs who deliver cancer care every day under real-world constraints — limited resources, delayed access, and structural challenges.
Key message:
When radiotherapy is delayed, inverting the PORTEC protocol — starting with chemotherapy, followed by radio-chemotherapy — is a safe and effective alternative.
Our results:
• 92% 5-year overall survival when timelines are respected
• Excellent locoregional control, despite the inverted sequence
This is about acting early, treating micrometastatic disease, and not letting delays decide our patients’ outcomes.
High-quality care is possible — even in resource-limited settings — when protocols are adapted, pragmatic, and rigorously applied.
Inverted PORTEC works. When done right.
Grateful to Prof. Salem Chouaib for the Special Issue
“Evolution of Cancer Therapies: Access of Developing Countries to Modern Oncology”
for giving visibility — and a scientific voice — to our realities.
Ariana’s pride. Tunisian pride.
A 100% Tunisian paper, driven by the belief that science has no borders.”
Title: When Standards Meet Reality: An Inverted PORTEC-3 Protocol for High-Risk Endometrial Cancer in Resource-Limited Settings
Authors: Raouia Ben Amor, Ines Mlayeh, Amal Riahi, Zeineb Naimi, Myriam Saadi, Rihab Haddad, Ghada Bouguerra, Awatef Hamdoun, Lilia Ghorbel, Nesrine Mejri Turki, Lotfi Kochbati

More posts on Endometrial Cancer.