Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
PYGO2 is overexpressed in myeloma pts w/ 1q21 amplification, driving plasma cell proliferation and cell cycle progression via canonical Wnt/TCF target genes and the replication stress and DNA damage response transcriptome.”
Title: PYGO2 is overexpressed in multiple myeloma patients with 1q21 amplification, driving plasma cell proliferation and cell cycle progression
Authors: Nicolas Thomas Iannozzi, Paola Storti, Rosanna Vescovini, Camilla Sitzia, Andrea Poletti, Valentina Franceschi, Giannalisa Todaro, Gabriella Sammarelli, Denise Toscani, Vincenzo Raimondi, Mattia Dessena, Oxana Lungu, Fazel Mohammadi, Matteo Scita, Matia Bernardi, Anna Benedetta Dalla Palma, Stefania Ricci, Bruno Lorusso, Costanza Anna Maria Lagrasta, Federico Quaini, Luca Agnelli, Gaetano Donofrio, Nicola Giuliani
You can read the Full Article on Cancer Gene Therapy.
You can find other articles featuring Robert Orlowski on OncoDaily.
