Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Rapid peak cilta-cel expansion is associated with delayed neurotoxicity (DNT) in myeloma; peak ALC ≥3000/uL, or ≥2500/uL following a daily twofold increase, predicted elevated DNT risk (sensitivity 81%, specificity 59%).”
Title: Rapid Peak Cilta-cel Expansion is Associated with Delayed Neurotoxicity in Multiple Myeloma
Authors: Hitomi Hosoya, Arash Velayati, Danai Dima, Alexandria Jensen, Andrew J. Portuguese, Vanna Hovanky, Lekha Mikkilineni, Lauren C. Peres, Ariel F. Grajales-Cruz, Sylvester Homsy, Masooma Shifa Rana, Juancarlos Cancilla, Sunita Patil, Bita Sahaf, Theresa Latchford, Ciara L. Freeman, Brian J. Scott, Kun Wei Song, Omar Alexis Castaneda-Puglianini, Humza Khan, Saurabh Dahiya, Frederick L. Locke, Crystal L. Mackall, David B. Miklos, Rahul Banerjee, Doris K. Hansen, Melissa Alsina, Surbhi Sidana
You can read the Full Article on Blood.
You can find other articles featuring Robert Orlowski on OncoDaily.
