Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Single-cell multiomics reveals regulatory mechanisms of CAR T-cell persistence and dysfunction in myeloma, with/ CAR T cells infiltrating BM exhibiting a more activated and exhausted phenotype than their PB counterparts.”
Title: Single-cell multiomics reveals regulatory mechanisms of CAR T-cell persistence and dysfunction in multiple myeloma
Authors: Lorea Jordana-Urriza, Guillermo Serrano, Sergio Camara-Peña, Maria E. Calleja-Cervantes, Patxi San Martin-Uriz, Aintzane Zabaleta, Aina Oliver-Caldes, Marta Español-Rego, Diego Alignani, Teresa Lozano, Saray Rodriguez-Diaz, Elena Iglesias, Valentin Cabañas, Juan L. Reguera, Veronica Gonzalez-Calle, Maria V. Mateos, Fermin Sanchez-Guijo, Bruno Paiva, Juan J. Lasarte, Susana Inoges, Ascension Lopez-Diaz de Cerio, Azucena Gonzalez-Navarro, Manel Juan, Carlos Fernandez de Larrea, Esteban Tamariz, Ana Alfonso-Pierola, Paula Rodriguez-Otero, Jesus F. San-Miguel, Mikel Hernaez, Juan R. Rodriguez-Madoz, Felipe Prosper
You can read the Full Article in Blood Neoplasia.

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