Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Systematic review and meta-analysis concludes immunofixation (SIFE and UIFE) and sFLC ratio combined give sensitivity of 0.99 (0.96-1.00)) as reliable initial testing strategy to raise suspicion of diagnosis of AL amyloidosis.”
Title: Diagnostic Utility of Immunofixation and Free Light Chain Assay in AL Amyloidosis: A Systematic Review and Meta-analysis
Authors: Muayad Azzam, Qais Hamarsha, Hassan Kawtharany, Jamil Nazzal, Aseel Alkhader, Tala Khraise, Mohammad M AlMasri, Hadi K. Abou Zeid, Iktimal Alwan, Nour Jaber, Matthew D Seftel, Maria Adela Aguirre, Deborah Boedicker, Naresh Bumma, Antonia S. Carroll, Raymond Comenzo, Joselle Cook, Noel R Dasgupta, Alfredo De La Torre, Angela Dispenzieri, Faizi Jamal, Jack Khouri, Maria M Picken, Shahzad Raza, Nelson Leung, Vaishali Sanchorawala, Nitasha Sarswat, Hira Shaikh, Daulath Singh, Vishal Kukreti, Reem A. Mustafa
You can read the Full Article in Blood Advances.

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