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Mustafa Özdoğan: A Landmark Step Forward for Patients with Leptomeningeal Metastasis

Mustafa Özdoğan, Head of Division of Medical Oncology at Memorial Cancer Center, shared a post on X:

“Proton therapy has long strived for a solid role in oncology.

Now, high-quality evidence is emerging.

A randomized phase II trial in JAMA Oncology shows proton craniospinal irradiation (pCSI) significantly improves CNS PFS (8.2 vs 2.3 mo) and OS (11.3 vs 4.9 mo) compared with photon IFRT in the daunting setting of leptomeningeal metastases.

A landmark step forward for a disease with few options.”

Title: Proton Craniospinal Irradiation for Patients With Leptomeningeal Metastasis

Authors: Yang, Jonathan T., Yerramilli, Divya, Pentsova, Elena, Wolden, Suzanne, Young, Robert J., Correa, Denise D., Imber, Brandon S., Wijetunga, N. Ari, Goglia, Alexander G., Zhang, Zhigang, Zheng, Junting, Baser, Raymond, Bernstein, Ashley, Kratochvil, Leah, Xiao, Julie, Hattangadi-Gluth, Jona, Miller, Alexandra M., Wilcox, Jessica A., Betof Warner, Allison, Yu, Helena, Kris, Mark G., Seidman, Andrew D., Powell, Simon N., Boire, Adrienne

Read The Full Article at JAMA Oncology.

Mustafa Özdoğan: A Landmark Step Forward for Patients with Leptomeningeal Metastasis

More Posts Featuring Proton Therapy.

Adrienne Alexander G. Alexandra M. Allison Andrew D. Ashley Baser Bernstein Betof Warner Boire Brandon S. cancer Correa Denise D. Divya Elena Goglia Hattangadi-Gluth Helena Imber JAMA Oncology Jessica A. Jona Jonathan T. Julie Junting Kratochvil Kris Leah Mark G. Miller Mustafa Özdoğan N. Ari OncoDaily Oncology Pentsova Powell proton therapy Raymond Robert J. Seidman Simon N. Suzanne Wijetunga Wilcox Wolden Xiao Yang Yerramilli young Yu Zhang Zheng Zhigang