Mostafa Faisal, Adjunct Assistant Professor at Alfaisal University, shared a post on X about recent paper published in British Journal of Hematology:
“Integration of genomic and clinical variables improves the prediction of myelodysplastic syndromes to acute myeloid leukaemia transformation and prognosis.
MDS (China, n=437): New genomic models outperform IPSS-R/M. AML transformation predicted by BM blasts %, KRAS, STAG2, TP53. Validated OS & PFS models using age/sex + key mutations (TP53, TET2, SF3B1). Stratifies pts into 4 risk groups → better prognosis & treatment guidance.”
Title: Integration of genomic and clinical variables improves the prediction of myelodysplastic syndromes to acute myeloid leukaemia transformation and prognosis
Authors: Huimin Jin, Zhen Guo, Liying Zhu, Fei Huang, Yujie Wu, Hairong Qiu, Yan Wang, Yuemin Gong, Guangsheng He, Lei Fan, Zhongxun Shi, Wenyi Shen, Chun Qiao
You can read the full article in British Journal of Hematology.
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