Miguel Martín, Emeritus Professor of Medicine at Universidad Complutense, Madrid, shared on LinkedIn:
“This GEICAM study suggests that low endocrine transcriptional activity measured by the SET ER/PR index can predict which chemotherapy regimen would offer survival benefit for an individual patient. SET ER/PR index is the first genomic assay that seems able to o predict benefit from taxane-based chemotherapy.”
Title: Sensitivity to Endocrine Therapy Index Predicts Benefit from Weekly Adjuvant Paclitaxel for Hormone Receptor–Positive Breast Cancer in the GEICAM/9906 Trial
Authors: Miguel Martín, Alvaro Rodriguez-Lescure, Cristina Reboredo, Eveline Chen, Manuel Ruiz-Borrego, Ana Santaballa Bertran, Cesar A. Rodríguez, Noelia Martinez-Jañez, Emilio Alba, Kevin Tran, Ignacio Pelaez Fernandez, Isabel Álvarez, Miguel A. Seguí, Alberto de la Cruz, Vicente Valero, Antonio Antón-Torres, Raquel Andrés, Kepa Amillano, José J. Ponce-Lorenzo, Severina Dominguez Fernandez, Jesus Herranz, Raul Rincon, Rosalía Caballero, Angel Guerrero-Zotano, Federico Rojo, W. Fraser Symmans
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