Michaël Pierrelée, Danish Cancer Institute
Danish Cancer Institute/LinkedIn

Michaël Pierrelée Explains How Autophagy Regulates RNA – Danish Cancer Institute

Danish Cancer Institute shared a post on LinkedIn:

“Meet the scientist – Michaël Pierrelée, Ph.D.

Michaël Pierrelée is a postdoctoral researcher in Lisa Frankel’s Homeostasis and Recycling Group, where he studies how autophagy regulates RNA – the molecules that act as intermediaries between genes and proteins. This research contributes to a deeper understanding of how gene expression is controlled in both healthy and diseased cells.

Autophagy is a cellular recycling process that helps maintain balance and becomes particularly active under stress or in disease. It can either suppress or support tumour growth, depending on the context, and is also linked to aging and neurodegeneration. Michaël uses RNA sequencing to investigate how autophagy influences gene regulation and cellular behavior.

‘All genes and subsequent mechanisms work together to create a functional cell. To truly understand disorders, it is necessary to explore these dysregulated mechanisms when the cell becomes dysfunctional.’

Michaël explains.

Originally from France, Michaël studied biotechnology in Paris and Strasbourg, followed by a PhD in bioinformatics in Marseille. He moved to Denmark for a postdoc at DTU and later joined Lisa Frankel’s group to work more closely with experimental researchers.

‘I am very much looking forward to working at the Danish Cancer Society’s Center for Cancer Research. I am especially excited to get to know my many new colleagues better.’

Says Michaël.

Welcome to the DCI, Michaël – we’re pleased to have you on board.”

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