Mashukur Rahman: Is ‘Inoperable’ Becoming an Outdated Term in Liver Oncology?
Mashukur Rahman/LinkedIn

Mashukur Rahman: Is ‘Inoperable’ Becoming an Outdated Term in Liver Oncology?

Mashukur Rahman, Resident Doctor at Bangladesh Medical University, Medical Officer at Directorate General of Health Services, shared a post on LinkedIn:

‘Is ‘Inoperable’ becoming an outdated term in Liver Oncology?

A few years ago, a diagnosis of high-risk, large-volume Hepatocellular Carcinoma (HCC) was often a terminal conversation.

The tumors were too big for surgery and too advanced for a transplant.

But the ‘Glass Ceiling’ of liver cancer treatment is finally breaking.

I recently reviewed a case that perfectly illustrates this shift. They used a ‘Double-Whammy’ approach:

  1. Systemic Immunotherapy: To prime the immune system and attack the cancer globally.
  2. Targeted Interventional Radiology (IR): Using precision strikes like TACE/TARE to kill the tumor from within.

The Result?

Complete Downstaging.

What was once a massive, life-threatening mass shrunk and stabilized to the point where the patient moved from ‘Palliative Care’ to ‘Curative Surgery’ eligibility.

The Lesson:

We are moving away from ‘Siloed Medicine.’ The future isn’t just a better drug or a better surgery—it’s the synergy between the Oncologist, the Interventional Radiologist, and the Surgeon.

Are you seeing Immunotherapy change your surgical ‘No’ into a ‘Yes’? Let’s discuss the latest protocols in the comments.”

Mashukur Rahman: Is 'Inoperable' Becoming an Outdated Term in Liver Oncology?

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