Mark Lewis, Director of Gastrointestinal Oncology at Intermountain Healthcare in Utah, shared a post on X:
“Since leucovorin is trending I’ll resurface this thread and observe that I’ve practiced GI oncology during multiple shortages of the drug that forced me to ask when it was truly essential for my patients (and also made me aware of the ~10x cost of substituting levoleucovorin!).”
Quoting his own post below:
“WHY I (ALMOST) NEVER BOLUS 5-FLUOROURACIL.
I’ve been pondering this thread for a while but it’s become more urgent in light of another looming chemo shortage <deep sigh>, this time with an imminent dearth of THE foundational drug of GI oncology: 5-fluorouracil, or 5-FU.”
More from Mark Lewis on OncoDaily.