Mainak Bardhan, Doctoral Researcher at Howard Hughes Medical Institute-University of Miami Miller School of Medicine, shared a recent article he and his colleagues co-authored, on LinkedIn, adding:
“Excited to share our new publication titled ‘Polymorphism of Melanocortin Receptor Genes – Association with Inflammatory Traits and Diseases’
Read here.
Melanocortin receptors (MCRs) are much more than skin pigmentation and appetite regulation – they influence inflammation, immunity, and disease risk such as melanoma, familial glucocorticoid deficiency, obesity, type 2 diabetes, and major depressive disorder.
We explored:
- How genetic variations in MC1R–MC5R contribute to conditions like melanoma, obesity, diabetes, and depression
- The role of MCRs in inflammatory diseases (e.g., MS, IBD, Alzheimer’s, arthritis)
- The growing pipeline of MCR-targeted therapies, with several already FDA-approved
These insights highlight MCRs as a powerful bridge between genetics, inflammation, and therapeutic innovation.”
Title: Polymorphism of Melanocortin Receptor Genes – Association with Inflammatory Traits and Diseases.
Authors: Mainak Bardhan, Ayush Anand, Amaan Javed, Maria Andrea Chilo, Nida Khan, Tulika Garg, Arihant Surana, Helen Huang, M. M. Samim, Vinay Suresh, Abhinav Khare, Bindu Menon, Tithishri Kundu.
Read the Full Article on Diseases.
Read more posts featuring Mainak Bardhan on OncoDaily.