Lung Cancer Europe shared post on LinkedIn:
“Immunotherapy has changed what’s possible for many people with lung cancer, but it doesn’t always keep working.
Understanding why remains a major research focus.
A new study in Nature explores how immune cells (T cells) can wear out over time, losing strength against cancer. The research points to a form of ‘protein stress’ that builds up inside these cells, limiting how well they can keep fighting tumours.
For people with lung cancer, this highlights a real challenge: scientific progress is moving fast, but people can only benefit if new treatments, and the research behind, them are accessible everywhere.
Title: Proteotoxic stress response drives T cell exhaustion and immune evasion
Autores: Yi Wang, Anjun Ma, No-Joon Song, Ariana E. Shannon, Yaa S. Amankwah, Xingyu Chen, Weidong Wu, Ziyu Wang, Abbey A. Saadey, Amir Yousif, Gautam Ghosh, Jay K. Mandula, Maria Velegraki, Tong Xiao, Haitao Wen, Stanley Ching-Cheng Huang, Ruoning Wang, Christian M. Beusch, Abdelhameed S. Dawood, David E. Gordon, Mohamed S. Abdel-Hakeem, Hazem E. Ghoneim, Gang Xin, Brian C. Searle, Zihai Li.
Read full article here.
More posts featuring Lung Cancer Europe on OncoDaily.