Laura Cogrossi, Postdoctoral Researcher at Cancer Research UK Manchester Institute, shared a post on LinkedIn about a recent article she and her colleagues co-authored, adding:
“I’m very proud to share that the work from my PhD has just been published
Check out how microbiota modulation can delay disease progression and enhance immunotherapy in multiple myeloma. Our findings show not only improved efficacy, but also a reduction in inflammatory events typically associated with immunotherapy, achieved by restraining IL-17–producing T cells.
It has been a great journey, guided by Matteo Bellone together with all the lab members who have contributed over the years, Anna Policastro, Paola Zordan, Marco Lorenzoni, Matteo Grioni, Benedetta Mattorre, Greta Meregalli.
And thanks to all our amazing collaborators.
Proud of what we achieved together, and excited for the next steps!”
Title: Microbiome modulation uncouples efficacy and toxicity induced by immune checkpoint blockade in mouse multiple myeloma
Authors: Laura Lucia Cogrossi, Anna Policastro, Paola Zordan, Matteo Grioni, Anna Tosi, Nathalie Rizzo, Benedetta Mattorre, Marco Lorenzoni, Greta Meregalli, Sofia Sisti, Francesca Sanvito, Alessandro Palmioli, Cristina Airoldi, Aurora Maurizio, Marta Chesi, Leif Bergsagel, Nicola Clementi, Antonio Rosato, Matteo Bellone
Read the Full Article on Nature Communications
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