Kefah Mokbel, Chair of Breast Cancer Surgery at London Breast Institute and Honorary Professor of Medicine at Cardiff University School of Medicine, shared a post on LinkedIn:
“A new prospective clinical study shows that whole-body 18F-FDG PET-CT detected all cases of distant metastatic disease in patients with locally advanced invasive lobular breast cancer (ILBC), outperforming conventional staging with CT and bone scan alone.
In this high-risk cohort, PET-CT upstaged ~13 % of patients to stage IV, including cases not identified on other imaging modalities. Importantly, some ILBC tumors had low FDG uptake, highlighting biological heterogeneity and the need for thoughtful interpretation.
These findings support the value of PET-CT in accurate staging and personalized management of advanced lobular breast cancer, with potential implications for treatment planning and outcomes.”
Title: Prospective study on 18F-FDG PET-CT for staging locally advanced invasive lobular breast carcinoma
Authors: Ur Metser, Ian S. Dayes, Sameer Parpia, Andrea F. Eisen, Nicole Hodgson, Tulin D. Cil, Ralph George, Phillip Blanchette, Angel Arnaou, Adrien Chan, Mark N. Levine
Read The Full Article
Other articles about PET-CT on OncoDaily.