Karamvir Yadav shared a post on X:
“New study out, which is telling: We’ve been oversimplifying BRCA1.
BRCA1 mutation ≠ uniform PARPi sensitivity.
- Domain-based stratification improves prediction
- Mutation topology influences PFS
- Functional annotation should guide interpretation
Time to move beyond “pathogenic vs non-pathogenic.” ”
Other articles featuring Karamvir Yadav on OncoDaily.