Joana Janela Jacinto, Medical Oncology Resident at Local Health Unit of Trás-os-Montes and Alto Douro, shared on LinkedIn:
“It was a very special moment to be part of the SIOG 2026 Annual Conference in Valencia!
SIOG is a global community of clinicians and researchers dedicated to improving care for older adults with cancer. Its Annual Conference brings together experts from around the world to share the latest advances in geriatric oncology, and being part of it was a truly enriching experience.
I presented two posters developed at Unidade Local de Saúde Trás-os-Montes e Alto Douro:
‘Adjuvant Chemotherapy in Older Patients with Colorectal Cancer: A Real-World Oncogeriatric Perspective on Treatment Duration and Intensity’ (P211)
Evidence on the optimal balance between efficacy and tolerability of adjuvant chemotherapy in older patients is still limited. In this retrospective study of 125 patients treated between 2020 and 2023:
- Peripheral neuropathy was more frequent with oxaliplatin-based regimens than with fluoropyrimidine monotherapy (30.8% vs 8.5%)
- Within the CAPOX group, overall toxicity was higher with 6 months than with 3 months of treatment (62.5% vs 23.5%)
- No clear survival benefit was observed with oxaliplatin or with longer treatment duration
In line with the IDEA trial, these results suggest that shorter strategies may be appropriate in selected older patients.
‘Chemotherapy Toxicity as a Driver of Treatment Disruption and Hospitalization in Oncogeriatric Patients’ (P217)
Chemotherapy-related toxicity is a major challenge in older patients, yet real-world data remain scarce. In the same cohort:
- Clinically relevant toxicity occurred in 36.1% of patients
- It was independently associated with dose reduction, treatment suspension, overall treatment disruption and hospitalization
If you would like to read more, the abstracts are published in the Journal of Geriatric Oncology, Volume 17, Issue 8, Supplement, November 2026.
I learned a lot from all the colleagues I met and from the different perspectives of each country. Thank you to everyone who took part in this project, and to everyone who stopped by to share feedback and ideas.
Hope to be back at the SIOG Annual Conference in 2027!”
You can also read: SIOG 2026: 15 Posts Not to Miss from the Annual Conference in Valencia
