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Jennifer Bires: Mental Health Impacts Cancer Outcomes
Aug 19, 2025, 10:45

Jennifer Bires: Mental Health Impacts Cancer Outcomes

Jennifer Bires, Executive Director of Life with Cancer and Patient Experience for the Inova Schar Cancer Institute, shared a post on LinkedIn:

“Mental Health Impacts Cancer Outcomes

We’ve known for some time that psychological stress plays a role in cancer.
But a new study takes that link further — showing how stress hormones can actually initiate and worsen cancer development at the cellular level, especially in those with BRCA1/2 mutations.

Here’s what the study found:
Cortisol (the primary stress hormone) damages DNA in breast epithelial cells
In people with BRCA1/2 mutations, cortisol delays DNA repair
Higher cortisol was associated with higher cancer risk in both women (breast cancer) and men (prostate cancer)

This builds on earlier evidence:

  • A meta-analysis of 165 longitudinal studies showed psychosocial factors increase cancer incidence, reduce survival, and raise mortality.
  • Another study tracking 163,000 people found those who felt high distress after diagnosis were 32% more likely to die from their cancer.

These aren’t soft statistics. They are biological truths.

So here’s the question:
Why do we continue to treat psychological care as “nice to have” instead of standard of care?

We must stop separating mind from body.
Mental health is not a support service, It is core prevention, especially for high-risk populations.
The infographic below to highlight what the science is telling us

Let’s make psychological support:

  • Equitable
  • Standard
  • Embedded across the continuum of cancer care

Because emotional well-being isn’t extra. It’s medicine.

How is your organization prioritizing mental health in prevention and survivorship?

Let’s share ideas — and challenge the status quo together.”No alternative text description for this image

More posts featuring Jennifer Bires on OncoDaily.