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Jean-Charles Soria: Lung Cancer 2030 – From Treating Disease To Intercepting Evolution
Jean-Charles Soria/gustaveroussy.fr

Jean-Charles Soria: Lung Cancer 2030 – From Treating Disease To Intercepting Evolution

Jean-Charles Soria, SVP and Oncology Therapeutic Area Head at Amgen, shared a post on LinkedIn:

“Lung cancer 2030: from treating disease to intercepting evolution

  • Evolution-guided care: integrate genomics + epigenome + proteome to map tumor trajectories
  • MRD- based trials: ctDNA-driven escalation/de-escalation – treat microscopic disease, not relapse
  • Target plasticity: drug-tolerant persisters & lineage switching as primary therapeutic targets
  • New modalities: ADCs, TCEs, degraders to expand beyond classic oncogene
  • Shift upstream: prevention (IL-1β axis), and risk-adapted screening

Future = anticipate, intercept, and adapt.”Jean-Charles Soria: Lung Cancer 2030 - From Treating Disease To Intercepting Evolution

Title: A Roadmap to Transform Lung Cancer Outcomes: Priorities in Biology, Therapeutic Innovation, Early Detection, Prevention and Interception

Authors: Monte M. Winslow, Mohamed A. Ahmed, Christine D. Berg, James R.M. Black, Julian Downward, Ramaswamy Govindan, Roy S. Herbst, John V. Heymach, Elizabeth M. Jaffee, Norbert Kraut, Miriam Merad, Matthew Meyerson, Tej Pandya, Katerina Politi, Arati V. Rao, Charles M. Rudin, Jean Charles Soria, Yuning J. Tang, Kwok-Kin Wong, Timothy A. Yap, Charles Swanton

Read the Full Article.

Jean-Charles Soria: Lung Cancer 2030 - From Treating Disease To Intercepting Evolution

Other articles featuring Jean-Charles Soria on OncoDaily.

Arati V. Rao cancer Charles M. Rudin Charles Swanton Christine D. Berg Elizabeth M. Jaffee James R. M. Black Jean-Charles Soria John V. Heymach Julian Downward Katerina Politi Kwok-Kin Wong Lung cancer Matthew Meyerson Miriam Merad Mohamed A. Ahmed Monte M. Winslow Norbert Kraut OncoDaily Oncology Ramaswamy Govindan Roy S. Herbst Tej Pandya Timothy A Yap Yuning J. Tang