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Ivan Zanoni
Ivan Zanoni/immunologyphd.hms.harvard.edu

Ivan Zanoni: “Every Cell Is an Immune Cell” – Fibroblasts Orchestrate Immunosuppressive Niches in Breast Cancer

Ivan Zanoni, Associate Professor at Harvard Medical School,  shared a post on X about a paper by Pasi A. Jänne et al. published in Immunity:

“Weekend Read! Every Cell Is An Immune Cell!

Riedel Mattavelli Helal and co show Immunity that fibroblasts in breast cancer metastatic lymph nodes sense tumor-derived TLR4 agonists to attract monocytes and form an immunosuppressive niche, favoring lung metastasis.”

Ivan Zanoni

Title: A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer

Authors:Greta Mattavelli, Moutaz Helal, Ana Cetkovic, Maximilian J. Krämer, Saskia-Laureen Herbert, Kilian Mielert, Tanja Schlaiß, Anna Frank, Emily Riemer, Mara John, Josefina del Pilar Martinez Vasquez, Laura Kindl, Jonathan J. Swietlik, Benedikt O. Gansen, Marion Krafft, Emilia Stanojkovska, Hanna Fischer, Ute-Susann Albert, Jonas Bauer, Murilo Delgobo, Arpa Aintablian, Haisam Alattar, Manfred B. Lutz, Felix Meissner, Thordur Oskarsson, Leo Rasche, Gustavo Ramos, Andreas Rosenwald, Achim Wöckel, Angela Riedel

Read The Full Article in Immunity.

Ivan Zanoni

More posts on OncoDaily.

Achim Wöckel Ana Cetkovic Andreas Rosenwald Angela Riedel Anna Frank Arpa Aintablian Benedikt O. Gansen cancer Emilia Stanojkovska Emily Riemer Felix Meissner Greta Mattavelli Gustavo Ramos Haisam Alattar Hanna Fischer immunity Ivan Zanoni Jonas Bauer Jonathan J. Swietlik Josefina del Pilar Martinez Vasquez Kilian Mielert Laura Kindl Leo Rasche Manfred B. Lutz Mara John Marion Krafft Maximilian J. Krämer Moutaz Helal Murilo Delgobo OncoDaily Oncology Saskia-Laureen Herbert Tanja Schlaiß Thordur Oskarsson Ute-Susann Albert