The IASLC 2025 Hot Topic in Basic and Translational Science: Unraveling Precancer and Early-Stage Lung Cancer meeting is a three-day event in Tokyo, Japan, dedicated to advancing the understanding and treatment of early lung cancer.
The meeting focuses on the molecular, genomic, transcriptomic, and immune mechanisms of early lung carcinogenesis. It aims to bridge the gap between basic science and clinical application by exploring emerging biomarker and diagnostic innovations (including liquid biopsies and AI) and discussing novel therapeutic pathways like targeted therapies and immunotherapy for the earliest stages of the disease.
Triparna Sen, Professor at The Ohio State University, shared some insights from the event:
Starting the IASLC 2025 Meeting
“I am excited to begin the International Association for the Study of Lung Cancer 2025 Meeting: Unraveling Precancer and Early-Stage Lung Cancer From Biology to Clinical Application, in Tokyo.
Over the next two days, we will focus entirely on the science, biology, and clinical translation of early-stage lung cancer. Honored to join global leaders in lung cancer research for this important discussion.
Here we go!
Session 1: Molecular Mechanisms of Early Lung Carcinogenesis- Genetics and Epigenetics.”
“Thrilled to kick off the IASLC 2025 Hot Topic in Basic and Translational Science Meeting: Unraveling Precancer and Early-stage Lung Cancer From Biology to Clinical Application, in Tokyo.
An exciting program ahead.”

“Excited to kick off the IASLC HT25 with my co-chair, Dr. Aaron Tan, opening keynote speaker Dr. Daniel Tan, and Special honored speaker- Dr. PC Yang.”

Thought-provoking and forward-looking opening keynote
“Thought-provoking and forward-looking opening keynote by Daniel Tan.
Key questions for the future of early lung cancer
- What early biological events drive progression
- How do we integrate imaging and biomarkers for risk prediction
- What treatments can intercept the disease at its start
- What systems enable equitable early detection and care?”

Fascinating talk by Dr. Hsuan Yu Chen
“Fascinating talk by Dr. Hsuan Yu Chen from National Taiwan University College of Medicine on The Genomic Impact of Environmental Carcinogens. Powerful insights into early-stage lung cancer biology.”

Excellent session by Hiroyuki Yasuda
“Excellent session by Hiroyuki Yasuda of Keio University School of Medicine on Transcription factor regulation in Lung Cancer.
Exceptional science and direction.”

Outstanding presentation by the session chair
“Outstanding presentation by session chair Dr. Ayako Suzuki from the University of Tokyo on Molecular implications of the stepwise progression of lung adenocarcinoma. Great momentum for HT25.”

Insightful talk by Young Seok Ju
“Insightful talk by Young Seok Ju of the Korea Advanced Institute of Science and Technology on Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma. Important advances for the field.”

Remarkable science shared by Dr. William Lockwood
“Selected from high-impact abstracts, remarkable science shared by Dr. William Lockwood from BCCRC on Fine Particulate Matter PM2.5 as a Driver of Genomic Alterations and Lung Tumour Initiation. Truly impactful work.”

Inspiring special session lecture by Dr. P.C. Yang
“Inspiring special session lecture at IASLC HT25 by Dr. P.C. Yang from National Taiwan University on the molecular mechanisms driving early lung cancer progression, especially EGFR-driven lung cancer.
A true leader in the field delivering breakthrough insights!”

“Starting Day 2 with a fascinating talk by Dr. Clare Weeden from The Walter and Eliza Hall Institute of Medical Research on occupational and environmental hazards associated with lung cancer.
Important insights for early detection.”

Exciting presentation by Dr. Kenichi Yoshida
“Exciting presentation by Dr. Kenichi Yoshida from the National Cancer Center Research Institute on tobacco smoking and somatic mutations in human bronchial epithelium.
Clear impact for lung cancer prevention.”

An engaging session by Dr. Robert Samstein
“An excellent and engaging session by Dr. Robert Samstein of Mount Sinai on risk factors associated with inherited genes. Strong science shaping risk assessment.”

You can find more posts featuring Triparna Sen on OncoDaily.