Henry C Fung, Chair and Professor, Department of Bone Marrow Transplant and Cellular Therapy at Fox Chase Cancer Center, shared a post on X:
“Landmark trials deserve landmark scrutiny.
The PERSEUS trial has transformed frontline treatment for transplant-eligible multiple myeloma and established a new standard of care.
But practice-changing does not mean scientific discussion should stop.
As clinicians and educators, we should distinguish observed evidence from model-based projections, MRD negativity from cure, and trial populations from real-world patients.
This PSNS Myth versus Truth summarizes six common misconceptions surrounding PERSEUS.
The goal is not to criticize a landmark trial.
The goal is to better understand it.
Great science welcomes thoughtful discussion.”

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