Hassan Hashmi, General and Colorectal Surgeon at Las Vegas Surgical Associates, shared a post on LinkedIn:
“A timely review from JAMA highlights a critical reality: obesity is not just a metabolic condition, it is a major oncologic risk factor.
With approximately 10% of new cancer diagnoses annually in the U.S. linked to obesity, and even higher proportions in cancers such as endometrial and hepatobiliary, this calls for a broader focus on prevention.
What stands out is the biology. Chronic inflammation, hormonal dysregulation, immune suppression, and microbiome alterations all converge to promote tumorigenesis.
This is particularly relevant in colorectal cancer too, where rising obesity rates parallel increasing incidence, including in younger patients.
Encouragingly, sustained weight loss of more than 10% may help reduce cancer risk.
As surgeons and clinicians, this reinforces that cancer prevention starts long before the endoscopy suite.”
Title: Obesity and Cancer, A Translational Science Review
Authors: Sherry Shen, Kristy A. Brown, Angela K. Green, Neil M. Iyenga
Read the full article on JAMA.
Other articles about Hassan Hashmi on OncoDaily.