Harish Nagaraj, Consultant and HOD Nuclear Medicine, MIC In-Charge at KUTRRH, shared a post on LinkedIn:
“Molecular imaging is not just about detection; it is about direction.
Transforming Lymphoma Care with Molecular Imaging.
Presenting a case of ‘Anaplastic lymphoma’ which shows the importance of FDG PET/CT in treatment response assessment.
The patient initially presented with:
- Extensive lymphadenopathy involving both sides of the diaphragm
- Predominant disease burden in the left upper hemibody.
- Associated pleural effusion and nodular involvement: Image A
- Following systemic chemotherapy, response evaluation demonstrated:
- Near complete metabolic and morphological resolution of previously involved sites: Image B
Residual areas of uptake corresponding to a Deauville score of 4, consistent with a partial metabolic response
This case underscores a critical point in lymphoma management:
- Structural imaging alone may underestimate response
- Metabolic imaging provides the nuance needed for accurate response categorization.
Such cases reinforce the value of precision imaging in optimizing patient outcomes and tailoring therapy.”
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