Giannis Mountzios: What happens to patients with st3 unresectable NSCLC who never receive maintenance IO?
Giannis Mountzios/LinkedIn

Giannis Mountzios: What happens to patients with st3 unresectable NSCLC who never receive maintenance IO?

Giannis Mountzios, Director of the 4th Oncology Department and Clinical Trials Unit at Henry Dunant Hospital Center, shared a post on X:

“What happens to patients with st3 unresectable NSCLC who never receive maintenance IO?

Just out in Clinical Lung our POSITION study:

  • N=2,076
  • 23% incomplete cCRT (A)
  • 12.7% PD within 42d post-cCRT (B)
  • mOS A=21.6m, B=10.1m
  • Black pts risk for incomplete cCRT
  • Vascular/renal disease risk for PD

1 out of 3 patients does not make it to the PACIFIC regimen… Those patients represent an unmet medical need and should enter clinical trials!”

Title: Characterizing Risk Factors and Outcomes in Patients with Unresectable, Stage III Non-Small-Cell Lung Cancer Who Do Not Complete, or Experience Progression During/Within 42 Days of Concurrent Chemoradiotherapy: The POSITION Study

Authors: Giannis Mountzios, Julius K. Weng, Eleni Zairi, Kristin Hsieh, Pratibha Chander, William Dunlop, Yao Qiao, Alice Wang, Adam Januszewski

Read the Full Article.

Giannis Mountzios: What happens to patients with st3 unresectable NSCLC who never receive maintenance IO?

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