George Vlachogiannis: Delirium as a high-impact prognostic signal in acutely hospitalized cancer patients
George Vlachogiannis/LinkedIn

George Vlachogiannis: Delirium as a high-impact prognostic signal in acutely hospitalized cancer patients

George Vlachogiannis, Managing Editor of Cancer Control at Sage, shared a post on LinkedIn:

“Incident Delirium in Hospitalized Cancer Patients: Clinical Factors Associated With Mortality and Prolonged Hospitalization

A new study from Moffitt Cancer Center and the University of South Florida published in Cancer Control highlights delirium as a high-impact prognostic signal in acutely hospitalized cancer patients, not just a transient complication.

In a retrospective cohort of 126 non-surgical oncology inpatients who developed incident delirium, in-hospital mortality was 15.9%, and non-survivors had longer delirium duration (3 vs 1 day) plus clear markers of physiologic vulnerability: low albumin, low platelets, low BMI, and higher LDH, along with higher rates of sepsis and greater pre-delirium benzodiazepine exposure. Delirium duration also tracked with longer length of stay, reinforcing delirium as a measurable indicator of declining resilience.

Early recognition of delirium plus rapid assessment of frailty, infection, nutrition, and sedative burden may offer actionable pathways to improve inpatient outcomes in oncology.”

Title: Incident Delirium in Hospitalized Cancer Patients: Clinical Factors Associated With Mortality and Prolonged Hospitalization

Authors: Brandon Dyer, Joel Kallarackal, Robert Baldwin, Aasha Hoogland, Kenneth Snell, Heather Jim, Jeffrey Huang

Read the Full Article.

George Vlachogiannis: Delirium as a high-impact prognostic signal in acutely hospitalized cancer patients

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