Geoffrey Buckle, Gastrointestinal Oncologist at UCSF Health, Associate Director for Priority Initiatives at UCSF Young-Onset Colorectal Cancer Program, shared a post on X:
“How generalizable is the evidence informing cancer care in sub-Saharan Africa?
Our new JCO Global Oncology study examined 2,931 studies cited in National Comprehensive Cancer Network Harmonized Guidelines for Sub-Saharan Africa. Just 2.4% of studies reporting recruitment geography included pts from the region.
Among studies reporting race/ethnicity, only 9.3% of participants were Black. And 98.8% of studies with sufficient country-level data recruited exclusively from high- or upper-middle-income countries.
Resource-adapted guidelines are essential, but adapting recommendations to available resources doesn’t necessarily address whether the underlying evidence is generalizable.
We need more locally generated evidence—and greater attention to generalizability in guideline development.”
Title: Evidence in National Comprehensive Cancer Network Harmonized Guidelines for Sub-Saharan Africa: A Meta-Research Analysis
Authors: Scott J. Swartz, Gwynn Spielman, Samrawit Agezew, Ayo S. Falade, Rebecca J. DeBoer, Mary Jue Xu, Glory F. Makupa, Rugengamanzi Eulade, Courtney Chau, Da Kyung Jung, Rohan D. Luhar, Pariswi Tewari, Alita Mrema, Katherine Van Loon, Geoffrey C. Buckle
Read the Full Article on JCO Global Oncology
You can also read: Clement Adebamowo at COGC 2026: Prevention, Access, and the Real Work of Community Care in Africa
