Flavio G Rocha, Flavio G Rocha, Hedinger Chair of Surgical Oncology and Physician-in-Chief at OHSU Knight Cancer Institute, shared a post by JAMA on X, adding:
“Orchestra trial confirms no benefit to debulking surgery for multi org metastatic CRC.”
Quoting JAMA‘s post:
“Research Summary: Among patients with multiorgan metastatic Colorectal Cancer, tumor debulking combined with systemic chemotherapy failed to provide a survival benefit over chemotherapy alone and resulted in higher rates of serious adverse events.”
Title: Tumor Debulking in Combination With Chemotherapy in Multiorgan Metastatic Colorectal Cancer
Authors: Elske C. Gootjes, Lotte Bakkerus, Anviti A. Adhin, Barbara M. Zonderhuis, Kathelijn S. Versteeg, Jurriaan B. Tuynman, Martijn R. Meijerink, Cornelis J. A. Haasbeek, Johannes H. W. de Wilt, Dirk J. Grunhagen, Ewoud J. Smit, John M. Primrose, John Bridgewater, Esther van Meerten, Jan-Willem B. de Groot, Mathijs P. Hendriks, Esther Oomen-de Hoop, Tineke E. Buffart, Cornelis Verhoef, Henk M. W. Verheul
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