Erika Hamilton, Chief Development Officer, Late Phase & Director, Breast Cancer Research Program at Sarah Cannon Research Institute, shared a post on X:
”DB05 update on ILD with T-DXd.
10% ILD, 2 cases fatal.
Radiation pneumonitis (RP) incidence ~ 30%.
Having ILD did not increases the chance of RP.
No diff in ILD based on sequential or concurrent radiotherapy.
Moderate renal dysfunction increases the risk ILD.”
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