Eduardo Bruera, Medical Doctor at MD Anderson Cancer Center, shared a post on LinkedIn:
“In cancer patients, 1 mg IV hydromorphone equals 2.5 mg oral hydromorphone and ~11.5 mg oral morphine equivalent. At doses ≥30 mg/day IV, a lower conversion ratio is needed, reflecting lower cross-tolerance.”
Title: The Conversion Ratio From Intravenous Hydromorphone to Oral Opioids in Cancer Patients
Authors: Akhila Reddy, Marieberta Vidal, Saneese Stephen, Karen Baumgartner, Sara Dost, Ann Nguyen, Yvonne Heung, Simeon Kwan, Angelique Wong, Imelda Pangemanan, Ahsan Azhar, Supakarn Tayjasanant, Edenmae Rodriguez, Jessica Waletich, Kyu-Hyoung Lim, Jimin Wu, Diane Liu, Janet Williams, Sriram Yennurajalingam and Eduardo Bruera.
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