Daniel Auclair, President of Hematocure, shared a post on X:
“ASH25 Late Breaking abstracts are out!
inMMyCAR, FIH of KLN-1010 in vivo BCMA CAR
Publication Number: LBA-1
Abstract Title: Minimal residual disease (MRD)-negative outcomes following a novel, in vivo gene therapy
generating anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR)-T cells in patients with
relapsed and refractory multiple myeloma (RRMM): Preliminary results from inMMyCAR, the first-inhuman phase 1 study of KLN-1010
Category: 700s – Transplantation and Adoptive Cell Therapies
Authors: Simon Harrison, Phoebe Joy Ho, Sueh-Li Lim, Stephanie Talam, Hannah Pahl, Dharmesh Dingar, Scott Currence, Travis Quigley, Andrew Spencer
Majestec-3 Ph.3 tec+dara vs investigator’s choice in RRMM
Publication Number: LBA-6
Abstract Title: Phase 3 randomized study of teclistamab plus daratumumab versus investigator’s choice
of daratumumab and dexamethasone with either pomalidomide or Bortezomib (DPd/DVd) in patients
(Pts) with relapsed refractory multiple myeloma (RRMM): Results of majestec-3
Category: 600s – Hematologic Malignancy
Authors: María-Victoria Mateos, Nizar Bahlis, Aurore Perrot, Ajay Nooka, Jin Lu, Charlotte Pawlyn, Roberto Mina, Gaston Caeiro, Alain Kentos, Vania Hungria, Donna Reece, Ting Niu, Anne Mylin, Charlotte Hansen, Raphael Teipel, Britta Besemer, Meletios Dimopoulos, Elena Zamagni, Satoshi Yoshihara, Kihyun Kim, Chang-Ki Min, Paulus Geerts, Elena Van Leeuwen-Segarceanu, Agata Tyczynska, Juan Luis Reguera, Magnus Johansson, Markus Hansson, Mehmet Turgut, Mark Grey, Surbhi Sidana, Paula Rodriguez-Otero, Joaquin Martinez-Lopez, Hamza Hashmi, Robin Carson, Rachel Kobos, Weili Sun, Kristen Lantz, Anne Seifert, Debbie Briseno-Toomey, Lisa O’Rourke, Maria Rubin, Diego Vieyra, Lijuan Kang, Luciano Costa
BRUIN-313, Ph. 3 pirto vs. BR in CLL/SLL
Publication Number: LBA-3
Abstract Title: Pirtobrutinib vs bendamustine plus rituximab (BR) in patients with CLL/SLL: First results
from a randomized phase III study Examining a non-covalent BTK inhibitor in untreated patients
Category: 600s – Hematologic Malignancy
Authors: Wojciech Jurczak, Michal Kwiatek, Jaroslaw Czyz, Ederson de Mattos, Ki-Seong Eom, Alexander Egle, Anna Panovská, Zhanet Grudeva-Popova, Hsuan-Jen Shih, Luis Felipe Casado Montero, Paolo Sportoletti, Vu Minh Hua, James D’Olimpio, Shinsuke Iida, Rodrigo Ito, Katherine Bao, Anne Fink, Weiji Su, Amy Ruppert Stark, Alejandro Levy, Tomasz Wrobel
VAYHIT2 Ph. 3 trial ianalumab plus eltrombopag versus placebo in ITP
Publication Number: LBA-2
Abstract Title: Primary results from VAYHIT2, a randomized, double-blind, phase 3 trial of ianalumab plus
eltrombopag versus placebo plus eltrombopag in patients with primary immune thrombocytopenia (ITP)
who failed first-line corticosteroid treatment
Category: 300s – Hemostasis, Thrombosis and Vascular Wall Biology
Authors: Hanny Al-Samkari, Adam Cuker, Francesco Zaja, Marc Michel, Waleed Ghanima, Thomas Stauch, Lei Zhang, Ming Hou, Thomas Zander, Azizan Sharif, Jing Sun, Uttam Kumar Nath, Roger Schutgens, Elena Rossi, Lien Deleu, Libor Červinek, Jae-Ho Yoon, Hung Chang, Theera Ruchutrakool, Masaki Iino, Tatsunori Goto, Patrick Urban, Justyna Fronczek, Matthew Foster, Marine Weill, Nicola Cooper
Ibmdx study: WG transcriptome in inherited BMF syndromes & related
Publication Number: LBA-4
Abstract Title: Whole genome transcriptome sequencing in inherited bone marrow failure syndromes
and related diseases – the ibmdx study
Category: 500s – Hematopoiesis
Authors: Lucy Fox, William Stevenson, Graham Lieschke, Nicole Den Elzen, Erin Goode, Vahid Pazhakh, Kelsey Man, Lin Cheng, Stephanie Best, Hasan Shamsi, Ella Thompson, Laura Barth, Simon Wu, Michelle Tan, Caroline Wong, Francis Baumgartner, Tracy Bryan, Cas Simons, Daniel MacArthur, Hadi Khorshidi, Juntao Lyu, David Ritchie, Mark Dawson, Anna Brown, Meg Wall, Paul James, Zornitza Stark, Erica Wood, Piers Blombery
Traction trial: tranexamic acid to reduce transfusions.
Publication Number: LBA-5
Abstract Title: A hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery:
The traction trial
Category: 400s – Transfusion Medicine
Authors: Brett Houston, Daniel McIsaac, Rodney Breau, Peter Greenstreet, Meghan Andrews, Sinzianna Avramescu, Hema Bagry, Robert Balshaw, Jayesh Daya, Kaitlin Duncan, Christopher Harle, Eric Jacobsohn, Tina Kerelska, Marshall Pitz, Paul Komenda, Sarah McIsaac, Tim Ramsay, Tarit Saha, Alan Tinmouth, Angela Recio, Dayna Solvason, Daniel Szoke, Marshall Tenenbein, Robert Talarico, Dean Fergusson, Ryan Zarychanski
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