Chrystal Paulos: New Insights into TH17 Biology Could Help Tune Immune Responses in Cancer
Chrystal Paulos/LinkedIn

Chrystal Paulos: New Insights into TH17 Biology Could Help Tune Immune Responses in Cancer

Chrystal Paulos, Professor and Co-leader of the Cancer Immunology Program at Winship Cancer Institute of Emory University, shared a post on LinkedIn:

“Grateful to be part of this new study on human Th17 biology with Anna Cole, PhD. Work led by Dr. Suman Mitra and an outstanding international team:
Aiolos and Eos drive distinct human TH17 functional states*
(Cellular and Molecular Life Sciences).

This work helps clarify how IkZF transcription factors shape inflammatory versus regulatory TH17 programs, with implications for cancer and autoimmunity: and opens interesting possibilities for therapeutically tuning these states.

Collaborations like this are where the field moves forward fastest. Thanks to Suman and colleagues for the opportunity to contribute. Looking forward to what comes next.”

Title: Aiolos and Eos drive distinct human TH17 functional states

Authors: Silvia Cerboni, Leila Mohammadnezhad, Komal Agrawal, Ramachandramouli Budida, Ilenia Papa, Silvia Gaggero, Joel Dulong, Anna Cole, Anja Mezger, Bingyu Yan, Zonghao Zhang, Elisabeth Israelsson, Petr Volkov, Songyuan Li, Eva F. Caceres, Malo Leprohon, Mojtaba Shekarkar Azgomi, Yue Cui, Svitlana Salemio, Mike Firth, Leif Wigge, Anna Rudin, Hanna Grindebacke, Marcello Maresca, Suman Mitra

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Chrystal Paulos: New Insights into TH17 Biology Could Help Tune Immune Responses in Cancer

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