Chinmay Jani, Chief Fellow of Hematology and Oncology at Sylvester Comprehensive Cancer Center at the University of Miami, shared a post on X:
“In our recent publication in JACC Journals, we describe a single-center case series of Triple M overlap syndrome (TMOS) from Sylvester Comprehensive Cancer Center following ICI – a rare but life-threatening combination of myocarditis, myositis, and myasthenia gravis.
Our series, led by Dr. Maria Osorio from Miller Medicine, highlights the rapid onset, high morbidity, frequent cardiac conduction abnormalities, and the need for early recognition and prompt escalation beyond corticosteroids.”
Title: Triple M Overlap Syndrome After Immune Checkpoint Inhibitors: A Case Series of a High-Mortality Phenotype
Authors: Maria F. Osorio, Alekhya Mitta, Fabricio Malaguez-Webber, Chinmay T. Jani, Marijo Bilusic, Jennifer Maning, Omar Wever-Pinzon, Yiannis S. Chatzizisis

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