CancerWorld shared on LinkedIn:
“What if cancer cachexia doesn’t start with metabolism, but with a signal from the tumour to the brain?
New research reveals a previously overlooked pathway:
Lkb1-mutant lung tumours can communicate directly with the brain through sensory nerves, triggering appetite loss and cachexia.
The findings could fundamentally shift how we understand and potentially treat this devastating syndrome.
Senior author Thales Papagiannakopoulos describes cachexia as a ‘neuro-metabolic syndrome’, pointing to potential interventions through drugs, diet, and neuromodulation.
Read the full news editorial by Janet Fricker.
Illustration by Lyana Gogyan.”
You can also read: How Do We Turn Policy Into Real, Equitable Change For Every Patient? – CancerWorld
