Bogda Koczwara, Director of Australian Research Centre for Cancer Survivorship, shared a post on LinkedIn:
“Did you know that in a review of 17 case control studies evaluating hypothalamic-pituitary-adrenal (HPA) axis in people with cancer, 16 showed dysfunction in people with cancer?
Why does it matter?
Because, HPA axis is responsible for stress response and HPA axis dysregulation in general population is associated with worse health outcomes including fatigue, disturbed sleep, subjective stress. Furthermore, HPA dysregulation can be a result of many cancer treatments including immunotherapy, which is increasingly an important part of cancer therapy.
Glad to see our review on this topic is one of the top viewed papers. We need more studies that uncover the mechanisms of symptoms that cancer survivors experience.”
Title: Hypothalamic-Pituitary-Adrenal Axis Dysfunction in People With Cancer: A Systematic Review
Authors: Natalie G. Kanter, Sarah Cohen-Woods, David Balfour, Morton G. Burt, Alison L. Waterman, Bogda Koczwara
Read The Full Article
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