Amol Akhade: LBA4 Abstract Shows OS Benefit With Ivosnescimab Plus Chemotherapy in Squamous NSCLC
Amol Akhade/LinkedIn

Amol Akhade: LBA4 Abstract Shows OS Benefit With Ivosnescimab Plus Chemotherapy in Squamous NSCLC

Amol Akhade, Senior Consultant Medical Oncologist and Hemato-Oncologist at Suyog Cancer Clinics and Reliance Hospitals, shared a post on X:

LBA4 – Ivosnescimab + chemotherapy improved OS vs tislelizumab + chemotherapy in untreated advanced squamous NSCLC:

  •  Median OS: 27.9 vs 23.7 months
  • HR 0.66 (34% reduction in risk of death)
  • PD-L1 <1%: HR 0.64
  • PD-L1 ≥1%: HR 0.68

In keynote 407 – pembrolizumab plus chemo median OS was 17.2 months.
End of An ERA?

Title: Ivonescimab plus chemotherapy versus tislelizumab plus chemotherapy in previously untreated advanced squamous non-small cell lung cancer: Overall survival results of the phase 3 HARMONi-6 trial.

Authors: Chen Zhiwei, Fang Yang, Yongzhong Luo, Longhua Sun, Lin Wu, Zhengxiang Han, Yun Fan, Yanqiu Zhao, Xing Ya Li, Haipeng Xu, Xiangjiao Meng, Ying Liu, Zhiye Zhang, Hui Luo, Qin Shi, Xuelei Ma, Xuezhen Ma, Zhongmin Zhang, Michelle Y. Xia, Shun Lu

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Amol Akhade: LBA4 Abstract Shows OS Benefit With Ivosnescimab Plus Chemotherapy in Squamous NSCLC

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