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What if You Could Lock Disease Biology Into Place? – Amgen
Aug 28, 2025, 15:40

What if You Could Lock Disease Biology Into Place? – Amgen

Amgen shared a post on LinkedIn:

“What if you could lock disease biology into place?

Amgen scientists are pioneering a potential new way to treat disease with LOCKTAC molecular glues that lock proteins together to control biological activity.

AMG 193 is one example of a LOCKTAC glue that is designed to selectively target tumor cells that have lost a gene called MTAP, with the goal of sparing healthy tissue. This potential first-in-class molecule is now in clinical trials.

Amgen’s innovative approach is now featured in Science Magazine. Read more about how Amgen is innovating in this space.”

More posts featuring Amgen.