Ahmet Dirican: Why Do RAS Inhibitors Fail to Deliver Durable Responses?
Ahmet Dirican/X

Ahmet Dirican: Why Do RAS Inhibitors Fail to Deliver Durable Responses?

Ahmet Dirican, Professor of Medical Oncology at Medicana International İzmir Hospital, shared a post on X:

  • “Why do RAS inhibitors fail to deliver durable responses?
  • Why does resistance develop so rapidly to KRAS G12C inhibitors?

A very insightful review revisits these fundamental questions.”

Title: Emerging landscape of KRAS inhibitors in cancer treatment: Cancer Cell

Authors: Jakob Riedl, Hiroyuki Matsubara, Reid McNeil, Parasvi Patel, Ferran Fece de la Cruz, Doga Gulhan, Ryan Corcoran

Read the Full Article.

Ahmet Dirican: Why Do RAS Inhibitors Fail to Deliver Durable Responses?