Global Colon Cancer Association (GCCA), posted on LinkedIn:
“Lynch Syndrome is the N 1 inherited cause of colorectal cancer — yet most families don’t know their risk.
Today is Lynch Syndrome Awareness Day.
Lynch Syndrome, caused by germline mutations in DNA mismatch repair genes, accounts for up to 25% of early-onset CRC cases. Approximately 1 in 279 individuals carry a pathogenic variant, and identification through genetic counselling and testing enables earlier surveillance — with screening recommended to begin at age 20–25 for confirmed carriers.
At the Global Colon Cancer Association (GCCA), we believe hereditary cancer risk identification should be standard of care, not an afterthought.
For clinicians: are you routinely assessing family history and referring for genetic counselling when CRC presents before age 50?
For patients identified as MSI-High through biomarker testing, genetic testing for Lynch Syndrome is also recommended — connecting this directly to treatment-relevant biomarker pathways.”
Other articles about Lynch Syndrome on OncoDaily.