Kal Tsanov
Kal Tsanov/X

Kal Tsanov: New Study on the Impact of Tumor Site on Driver Gene Mutations

Kal Tsanov, Assistant Professor at The University of Chicago, shared a post on X:

“Location, location, location! Now out in Nature Cancer, the final version of our study showing how a tumor’s anatomic site can impact the function of driver gene mutations, using SMAD4 inactivation in pancreatic cancer as a clin. relevant example.”

Title: SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence

Authors: Kaloyan Tsanov, Francisco Barriga, Yu-Jui Ho, Direna Alonso-Curbelo, Geulah Livshits, Sha Tian, Richard Koche, Timour Baslan, Janelle Simon, Alexandra Wuest, José Reyes, Jin Park, Wei Luan, John Wilkinson, Umesh Bhanot, Jordana Ray-Kirton, Ignas Masilionis, Nevenka Dimitrova, Christine Iacobuzio-Donahue, Ronan Chaligné, Dana Pe’er, Joan Massagué, Scott Lowe

Read the full article on Nature Cancer.

Kal Tsanov

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