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SENECA study summarized by Erman Akkus
May 28, 2024, 07:11

SENECA study summarized by Erman Akkus

Erman Akkus, Medical Oncology Fellow at Ankara University, shared a post on X:

FOLFIRI vs. CapTem in the second line after platinum/etoposid for NECs
SENECA study

The two regimens showed comparable activity

  • GEP and lung NECs
  • 12 weeks-Disease Control Rate 39.1% vs 28%
  • 12 mo OS 28.4% vs 32.4%
  • FOLFIRI: neutropenia, anemia
  • CapTem: thrombocytopenia, nausea/vomiting

The study was halted for futility as the minimum 12w-DCR threshold of 10 out of 25 patients was not reached.

Erman Akkus

Source: Erman Akkus/X