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Stephen V Liu: Early ctDNA Dynamics in SCLC Show Prognostic Value in TAZMAN Trial
Aug 12, 2025, 17:56

Stephen V Liu: Early ctDNA Dynamics in SCLC Show Prognostic Value in TAZMAN Trial

Stephen V Liu, Director of Thoracic Oncology, Chief, Division of Hematology and Oncology, and Associate Professor at Georgetown Lombardi Comprehensive Cancer Center, shared a post on X about a paper by Carmela Ciardullo et al. published in Clinical Cancer Research:

“Early ctDNA dynamics in SCLC from the TAZMAN trial (n=31) at Clinical Cancer Research. Baseline ctDNA yielded somatic alterations in 96% of patients. ctDNA clearance had positive prognostic value and changes anticipated relapse before imaging. Possible pharmacodynamic marker?”

Title: Early ctDNA dynamics inform first-line therapy in patients with extensive-stage small cell lung cancer

Authors: Carmela Ciardullo, Luis Tobalina, T. Hedley Carr, Philip Szekeres, Silvija Kraljevic, Lauren Averett Byers, Giulia Fabbri

You can read the Full Article on Clinical Cancer Research.

Stephen V Liu: Early ctDNA Dynamics in SCLC Show Prognostic Value in TAZMAN Trial

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