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Donald McDonnell: A Summary of the Biology of Endocrine Therapy Resistance in Breast Cancer
Aug 8, 2025, 09:23

Donald McDonnell: A Summary of the Biology of Endocrine Therapy Resistance in Breast Cancer

Donald McDonnell, Professor at the Department of Pharmacology and Cancer Biology at Duke University School of Medicine, shared a post on LinkedIn about a recent article by François-Clément Bidard et al. published in NEJM:

“This is a very clear summary of the complex biology underlying resistance to endocrine therapies (aromatase inhibitors) in patients with breast cancer.”

Title: First-Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer

Authors: François-Clément Bidard, Erica L. Mayer, Yeon Hee Park, Wolfgang Janni, Cynthia Ma, Massimo Cristofanilli, Giampaolo Bianchini, Kevin Kalinsky, Hiroji Iwata, Stephen Chia, Peter A. Fasching, Adam Brufsky, Zbigniew Nowecki, Javier Pascual, Lionel Moreau, Shin-Cheh Chen, Nuri Karadurmus, Einav Nili Gal-Yam, Kyung Hae Jung, Sonia Pernas, Sasha McClain, Wei He, Teresa Klinowska, Cynthia Huang-Bartlett, Nicholas C. Turner

Read the Full Article on NEJM

Donald McDonnell: A Summary of the Biology of Endocrine Therapy Resistance in Breast Cancer

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