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Maximilian Merz: Splenomegaly, CAR T-Cell Therapy, Relapsed Myeloma
Jul 19, 2025, 15:44

Maximilian Merz: Splenomegaly, CAR T-Cell Therapy, Relapsed Myeloma

Maximilian Merz, Associate Attending Physician at Memorial Sloan Kettering Cancer Center, shared a post on LinkedIn about a paper he co-authored with his colleagues published in Transplantation and Cellular Therapy of ASTCT:

“Finally out in Transplantation and Cellular Therapy of ASTCT

Prognostic implications of splenomegaly in BCMA-directed CAR T-Cell therapy for relapsed myeloma.

Major shoutout to co–first authors Thomas Wiemers and Maximilian Ferle — the Dynamic Data Duo — for driving the predictive modeling and analytics that made this work possible.

Clear massages!

Splenomegaly significantly associated with:

  •  severe and prolonged thrombocytopenia
  •  higher metabolic tumor volumes from PET/CT
  •  elevated sBCMA levels
  • independent prognostic factor for PFS and OS

Yet another great collaboration between hematologists and radiologists from the Leipzig University and Universitätsklinikum Carl Gustav Carus Dresden.”

Title: Prognostic implications of splenomegaly in BCMA-directed CAR T-Cell therapy for relapsed myeloma

Authors: Thomas Wiemers, Maximilian Ferle, Jonas Ader, Veronika Sotikova, David Fandrei, Nora Grieb, Luise Fischer, Patrick Born, Heike Weidner, Song Yau Wang, Madlen Jentzsch, Georg-Nikolaus Franke, Carmen Herling, Klaus Metzeler, Marco Herling, Simone Heyn, Timm Denecke, Kristin Reiche, Uwe Platzbecker, Vladan Vucinic, Thomas Neumuth, Hans-Jonas Meyer, Maximilian Merz

Read the Full Article on Transplantation and Cellular Therapy of ASTCT

Maximilian Merz: Splenomegaly, CAR T-Cell Therapy, Relapsed Myeloma

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