A durable antitumor activity to atezolizumab was observed in a subset of penile cancer – Gustavo

Although failed to achieve, a durable antitumor activity to atezolizumab was observed in a subset of penile cancer.

Single-center, PhII study 32  treated w/ atezolizumab; 20 received additional RT: 1-y PFS (goal 35%)

RESULTs:

Median FU 29 m

Median OS was 11.3 m

1-yPFS 12.5 %

ORR 16.7% w/ 2 complete and 3 partial responders

PFS in hrHPV + tumors & high T cell infiltration

Source: Gustavo / Twitter