Science

Jun 16, 2025, 17:06

Carmen Criscitiello Highlights Strategies to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer

Carmen Criscitiello, Director of Precision Oncology Unit at IEO European Institute of Oncology, shared a post on Linkedin:

“Just published in Cancer Treatment Reviews!

We took a deep dive into one of the most pressing challenges in HR+/HER2– BC: resistance to CDK4/6i.

In this review, we explore:

Why resistance emerges

How to counter it with innovative combinations

What’s next in endocrine, targeted, and immune-based strategies

This work reflects a strong collaborative effort across leading institutions.”

Title: Overcoming resistance to CDK4/6 inhibitors in hormone receptor positive, HER2 negative breast cancer: Innovative combinations and emerging strategies

Authors: Federica Giugliano, Carmine De Angelis, Barbara Pistilli, Giulia Viale, Giampaolo Bianchini, Mario Giuliano, Luca Malorni, Beatrice Taurelli Salimbeni, Angela Esposito, Antonio Giordano, Timothy A. Yap, Giuseppe Curigliano, Carmen Criscitiello

You can read the Full Artcile on Cancer Treatment Reviews

Carmen Criscitiello Highlights Strategies to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer

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