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Yvonne Diaz: Combination of Alectinib and Bevacizumab Shows Promising Results in ALK+ NSCLC
Yvonne Diaz/ey.com
May 19, 2025, 16:02

Yvonne Diaz: Combination of Alectinib and Bevacizumab Shows Promising Results in ALK+ NSCLC

Yvonne Diaz, EY Global Media Relations and Social Media Director, shared a post on X:

“Promising signals from the ALEK-B ph 2 trial: combining alectinib with bevacizumab achieved 97.1% 12-mo PFS and median PFS of 39.6 months in ALK+ NSCLC.
Intracranial control also notably strong.
Could this combo help overcome resistance in more aggressive ALK variants?.”

Title: Alectinib in combination with bevacizumab as first-line treatment in ALK-rearranged non-small cell lung cancer (ALEK-B): a single-arm, phase 2 trial

Authors: Oscar Arrieta, Luis Lara-Mejía, Eduardo Rios-Garcia, Enrique Caballé-Perez, Luis Cabrera-Miranda, Maritza Ramos-Ramírez, David Dávila-Dupont, Andrés F. Cardona, Graciela Cruz-Rico, Jordi Remon, Alexandra Garcilazo-Reyes, Rafael Rosell

You can read the Full Article on Nature Communications.

Bevacizumab

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alectinib Alexandra Garcilazo-Reyes Andres F. Cardona Bevacizumab cancer David Dávila-Dupont Eduardo Rios-Garcia Enrique Caballé-Pérez Graciela Cruz-Rico Jordi Remon Luis Cabrera-Miranda Luis Lara-Mejía Lung cancer Maritza Ramos-Ramírez NSCLC OncoDaily Oncology Oscar Arrieta Rafael Rosell Yvonne Diaz
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