Paolo Tarantino: Happy to have worked with Sarah Sammons and Nancy Lin at the ph2 DATO-Base trial
Paolo Tarantino, Medical Oncologist and Research Fellow at the Dana-Farber Cancer Institute, shared a post by Sarah Sammons, Breast Medical Oncologist at the Dana-Farber Cancer Institute, on X/Twitter:
“One of the most impactful aspects about Antibody Drug Conjugates (ADCs) is their remarkable intracranial activity, seen with T-DM1 and T-DXd. No data is however available with Trophoblast cell surface antigen 2 (TROP2) ADCs.
Happy to have worked with Sarah Sammons and Nancy Lin at the ph2 DATO-Base trial of Dato-DXd for brain metastasis, now open at Dana-Farber Cancer Institute!”
Quoting Sarah Sammons’s post:
“Paolo Tarantino, Nancy Lin and I’s Investigator Sponsored Trial (IST) evaluating the efficacy of datopotamab deruxtecan in active breast cancer brain metastases and Leptomeningeal Disease (LMD) is open with 1st patient screened.”
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Source: Paolo Tarantino/X and Sarah Sammons/X